Functional characterization and evaluation of in vitro protective efficacy of murine monoclonal antibodies BURK24 and BURK37 against Burkholderia pseudomallei.

Burkholderia pseudomallei, the causative agent of melioidosis has been recognized by CDC as a category B select agent.Although substantial efforts have been made for development of vaccine molecules against the pathogen, significant hurdles still remain.With no licensed vaccines available and high relapse rate of the disease, there is a pressing ne

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Tension-induced binding of semiflexible biopolymers

We investigate Aluminum Ornament theoretically the effect of polymer tension on the collective behavior of reversibly binding cross-links.For this purpose, we employ a model of two weakly bending wormlike chains aligned in parallel by a tensile force, with a sequence of inter-chain binding sites regularly spaced along the contours.Reversible cross-

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Crown rust pathotypes determined on oats in the Czech Republic from 2004 to 2006 and reaction to oat cultivars

The Puzzle incidence of oat crown rust (Puccinia coronata var.avenae Fraser et Ledingham) pathotypes was recorded in the Czech Republic in 2004-2006.The virulence of collected 79 monopustule oat crown rust isolates was assessed on 23 differentials.High diversity was observed; the isolates possessed from 0 to 8 virulence genes.More than 80% of patho

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Impact of working conditions on the health of pharmacy workers

The analysis revealed factors that have an adverse effect on human health: artificial lighting (I =0.72); standing activity (I=0.63); monotonous movements Jams (I =0.56); prolonged work at the computer (I =0.55).It was found that many pharmacy workers have chronic diseases: vascular pathology (29.4%), musculoskeletal pathology (28.4%), gastrointest

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